... deconvolution to calculate insulin secretion rates and mathematical modeling to quantitate -cell function. ... In NGT, incretin-mediated insulin release oral glucose tolerance test ... a predominance of glucose - induced vs. incretin- mediated stimulation. ... Insulin secretion rates estimated by two mathematical . ......

The sensitivity of insulin secretion to the rate of glucose change was also increased. ... insulin sensitivity; C peptide deconvolution; mathematical model ......

J Clin Invest 51:2047-2059, 1972; Cerasi E, Fick G, Rudemo M: A mathematical model for the glucose induced insulin release in man. ......

Developing a Mathematical Model of Insulin release from Pancreatic ... Mitochondrial glutamate acts as a messenger in glucose - induced insulin exocytosis. ......

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A mathematical model of the mitochondrial NADH shuttles and anaplerosis in the .... Role of NADH Shuttles in Glucose - Induced Insulin Secretion From Fetal ......

Insulin granule trafficking in beta-cells: mathematical model of glucose - induced insulin secretion ... Insulin Vesicle Release : Walk, Kiss, Pause ... Then Run .... Ca2+ Influx Does Not Trigger Glucose - Induced Traffic of the Insulin ......

A mathematical model of the changes in plasma glucose and insulin ... the significant exercise induced effects are: increased glucose uptake rate by the ... Intense exercise had unique effects on both insulin release and its roles in ......

Glucose - induced insulin secretion in vivo is thus biphasic, with a similarly ..... hypothesis for packet storage of insulin and its mathematical modeling . ......

We present a mathematical model in which both electrical and metabolic ... loss often observed clinically may be due to an islet- induced embolism that caused ..... The standard glucose signal to insulin release pathway in beta cells is ......

Insulin release at the molecular level: Metabolic-electrophysiological modeling of the ... in a physiological regime, via the glucose - induced release of insulin . ... data into accurate mathematical descriptions might contribute to considerably clarify ... Under these perspectives, we model and computer- simulate the ......

Keywords: Mathematical modeling ; Bioenergetics; Cellular metabolism; ... Increases in lipolysis, and the resulting release of free fatty acids into the circulation, .... whereas CEACAM2 regulates glucose - induced insulin secretion. ......

How glucose stimulates the secretion of insulin has been a central question since ... transduction system is presented via mathematical modeling analysis. ... is important for understanding glucose - induced insulin secretion due to the ......

Thus, we suggest that the first phase of glucose - induced insulin release is due to ... We also thank Dr F. Sala for his help with the mathematical model . ......